On August 26th, the first Green Key Volumetric Printing Application Forum was held in PanYu Campus of Guangzhou Medical University. This conference is the first conference with the theme of " Volumetric printing technology applications" in China, which brings together the multidisciplinary direction of bioprinting, bioink, life science, regenerative medicine, and biomedical engineering to discuss the latest research and application progress in the field of bioprinting.
Products launch ceremony
At the meeting, Guangzhou Medical University jointly released the first commercial volumetric bioprinting equipment OrganSEC in China, and launched the first volumetric printing equipment control software (Haomiao) independently developed in China and released six commercial bioinks.
Principal Xingcun Zhao delivered a speech
In his speech, Principal Xingcun Zhao expressed his gratitude to many well-known experts and scholars, industry, enterprises and other people from all walks of life who gathered in Guangzhou Medical University for academic discussion. He pointed out that the university has always attached great importance to the transfer and transformation of scientific research achievements, and promoted it as an important task of "Double-First Class" construction, responded to the development needs of new fields and new tracks, and continuously improved the supply quality of scientific and technological achievements. Professor Maobin Xie's team from the School of Biomedical Engineering has developed innovative results of volumetric bioprinting equipment. This technology fills the gap in the field of volumetric bioprinting in China, greatly improves the printing efficiency and cell viability, and effectively improves the level of organoid based drug screening and clinical treatment, which is of great significance to the development of regenerative medicine and biomedical engineering and the improvement of people's health quality. It will have a positive impact on promoting the development of biomedical industry in the Guangdong-Hong Kong-Macao Greater Bay Area.
Vice-principal Lin Zhou presided over the opening ceremony of the forum
Launch ceremony site
OrganSEC is the first commercial volumetric bioprinting device in China, which uses a back projection algorithm based on holographic imaging projection technology and CT imaging principle. This technology can project two-dimensional slices of three-dimensional objects into a printing bottle rotating at a certain speed by a specific algorithm, so that the light-curing ink in the printing bottle can form three-dimensional objects in all directions at the same time. This technology solves the problems of slow printing speed and low cell viability of conventional layer-by-layer printing, and the technical indicators have reached the world's first class to fill the gap in China. OrganSEC will mainly target the organoid market, including organoid preparation, organoid based personalized medicine for cancer and organoid based drug screening, etc., and will provide accurate personalized medication guidance for cancer patients.
OrganSEC's advantages include:
（1）Ultra-fast printing: the cm-sized 3D (active) structure can be printed in 10-120 seconds.
（2）High cell viability: the cell survival rate after printing was >95%.
（3）High resolution printing: the printing resolution reached 50 microns.
（4）There was no contact between the printing system and the printed object, and no physical damage to the cells.
（5）The surface of the printed object was smooth, and the surface structure of the organ was realistically simulated.
（6）Sterile printing.
（7）The printing conditions are mild, and the visible light can be used to print at room temperature, which is more suitable for bioprinting.
Professor Maobin Xie introduced OrganSEC, the first commercial volumetric printing device in China
Haomiao software integrates the functions of control, calculation, parameter adjustment and so on. It has three special functions, such as printing model library, real-time online slicing and multi-file printing, which makes up for the blank of domestic volumetric printing control software.
Bioink is a material ink developed based on volumetric bioprinting, which is suitable for both volumetric printer and other light-curing printer. Professor Maobin Xie's team has developed six commercial bioprinting inks, including visualization GelMA bioink, visualization silk fibroin bioink, visualization silk sericin bioink, GelMA bioink, silk fibroin bioink and silk sericin bioink.
Achievement transformation strategic cooperation signing ceremony
At the meeting, Green Key Biotechnology and Newton Optical Research Institute signed a strategic cooperation agreement on achievement transformation. As the national research market partner, Newton Institute of Optics is responsible for the research market promotion and after-sales service support of volumetric printing equipment and biological ink. The expected target is to complete the sales of 200 units of equipment within 3 years, and complete the sales of 1000 units of equipment within 5 years, and achieve the goal of the first volumetric printing market share in China.
Professor Yong He from Zhejiang University delivered a report on "3D bioprinting: from organ model to organ reconstruction"
Professor Changshun Ruan, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, delivered a report on "3D bioprinting and tissue Engineering"
Professor Guosheng Tang from Guangzhou Medical University delivered a report on "3D bioprinting microgel and its application exploration"
Associate Professor Zeyu Luo from West China hospital of Sichuan University delivered a report on "3D bioprinting/microfluidics for musculoskeletal regeneration"
Professor Minfeng Chen from Jinan University delivered a report on "Research on the molecular mechanism and intervention strategy of organoid model promoting tumor drug resistance"
The member of Professor Huisheng Liu 's team from Guangzhou National Laboratory delivered a report on "Construction of physiologically active and functional trachea by volumetric 3D printing tissue engineering"
Bo Jiang, Director of strategic consulting of Guangdong Respiratory and Health Association, delivered a report on "Science Popularization Leading, breathing without worry -- Introduction of Guangdong Respiratory and Health Association"
Professor Xiaodong Cao from South China University of Technology presided over the report
During the expert lecture and discussion session, outstanding experts in the field of bioprinting from Guangzhou National Laboratory, Zhejiang University, Sichuan University, South China University of Technology, Jinan University, Shenzhen Institute of Advanced Technology of Chinese Academy of Sciences, Guangdong Respiratory and Health Society and other units shared their latest research results in this field.
Group photo of the leaders and guests attending the meeting